Valuation of the EQ-5D-5L in Taiwan
Journal
PLoS ONE
Journal Volume
13
Journal Issue
12
Date Issued
2018
Author(s)
Lin, H.-W.
Li, C.-I.
Chang, J.-Y.
Gau, C.-S.
Luo, N.
Simon Pickard, A.
Ramos Goñi, J.M.
Tang, C.-H.
Hsu, C.-N.
Abstract
© 2018 Lin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objectives To date, a value set for the EQ-5D-5L based on the health state preferences of the general Taiwanese population has not been available. This study aimed to develop a Taiwanese value set for EQ-5D-5L to facilitate health technology assessment for medical products and services. Methods An international standardized protocol for EQ-5D-5L valuation studies developed by the EuroQol group was adopted. Adult members of the general public were recruited from six geographic regions in Taiwan. In computer-based face-to-face interviews, each participant completed 10 composite time trade-off (C-TTO) tasks and 7 discrete choice experiment (DCE) tasks. The C-TTO and DCE data were modeled alone or in combination (using hybrid models) with additive models containing 20 dummy variables as main effects. The model performance was assessed both quantitatively and qualitatively (mainly logical consistency and prediction patterns). Results Of 1,073 recruited participants, 1,000 completed the study. Approximately 13% of observed utility values were -1 in the C-TTO tasks. The hybrid model, using all available data that assumed C-TTO response values left-censored at -1 and with main effects coefficients with logical consistency (monotonicity), was considered as the most appropriate model. The predicted utility ranged from -1.0259 to 1. Conclusions An EQ-5D-5L value set was developed for Taiwan using an established study protocol and a representative sample of the general population. This may facilitate health economic evaluations and decision making on resource allocation under Taiwan’s national health insurance program in the future.
SDGs
Other Subjects
adult; article; biomedical technology assessment; controlled study; decision making; economic evaluation; female; human; human experiment; interview; major clinical study; male; national health insurance; population; prediction; quantitative analysis; resource allocation; Taiwan; evaluation study; health status; middle aged; patient preference; procedures; public health; quality of life; questionnaire; statistics and numerical data; Taiwan; young adult; Adult; Decision Making; Female; Health Status; Humans; Male; Middle Aged; National Health Programs; Patient Preference; Quality of Life; Surveys and Questionnaires; Taiwan; Technology Assessment, Biomedical; Young Adult
Publisher
PUBLIC LIBRARY SCIENCE
Type
journal article