Neurocutaneous melanosis with epilepsy: Report of one case
Journal
Acta Paediatrica Taiwanica
Journal Volume
42
Journal Issue
2
Pages
108-110
Date Issued
2001
Author(s)
Abstract
Neurocutaneous melanosis is a rare congenital syndrome characterized by the association of large or multiple congenital melanocytic nevi and benign or malignant melanotic tumors in the central nervous system. Patients with neurocutaneous melanosis usually have neurological symptoms early in life that progress rapidly due to the development of increased intracranial pressure or malignant melanoma. We report a 2-month-old female infant with multiple congenital melanocytic nevi and frequent seizure attacks. Magnetic resonance imaging of the brain demonstrated several regions compatible with melanotic deposits. During follow-up for one year, she had normal development and was seizure-free under the treatment of phenobarbital and valproic acid. We suggest that infants with large or multiple congenital melanocytic nevi should receive regular clinical check-up and brain imaging to exclude the possibility of central nervous system lesions.
Subjects
Congenital melanocytic nevus; Epilepsy; Neurocutaneous melanosis
SDGs
Other Subjects
phenobarbital; valproic acid; article; case report; central nervous system; clinical feature; disease association; disease course; epilepsy; female; follow up; human; infant; intracranial pressure; melanocytic nevus; melanoma; melanosis; neurologic disease; nuclear magnetic resonance imaging; phakomatosis; seizure; Epilepsy; Female; Humans; Infant; Melanosis; Neurocutaneous Syndromes
Type
journal article