One-Step Signal Amplified Gold Nanoparticles for Bacterial Infection Diagnosis on Lateral Flow Immunoassay Device
Journal
MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISBN
9781733419048
Date Issued
2022-01-01
Author(s)
Chien, Yuh Shiuan
Abstract
We established a high-sensitivity multiplexed bacterial detection system. The sensitivity of the lateral flow system is increased by using copper deposition signal amplification technology to simultaneously detect the Protein A of Staphylococcus aureus and the Exotoxin A of Pseudomonas aeruginosa. The experimental results show that the copper deposition signal amplification technology can effectively improve the sensitivity by about an order of magnitude. Compared with the standard system, the error of the light intensity detection device is within 5%. This system can implement the purpose of the rapid screening system more effectively.
Subjects
Copper Deposition-induced Signal Amplify | Exotoxin A | Lateral Flow Immunoassay Test | Protein A | Pseudomonas aeruginosa | Staphylococcus aureus
Type
conference paper