Convergence of non-communicable diseases and tuberculosis: A two-way street?
Journal
International Journal of Tuberculosis and Lung Disease
Journal Volume
22
Journal Issue
11
Pages
1258-1268
Date Issued
2018
Author(s)
Abstract
The intersection of tuberculosis (TB) with non-communicable diseases (NCDs), including diabetes mellitus (DM), chronic lung disease (CLD), and cardiovascular disease (CVD), has emerged as a critical clinical and public health challenge. Rapidly expanding NCD epidemics threaten TB control in low- and middle-income countries, where the prevention and treatment of TB disease remain a great burden. However, to date, the notion that TB may adversely impact NCD risk and severity has not been well explored. This review summarizes biomedical hypotheses, findings from animal models, and emerging epidemiologic data related to the progression of DM, CLD and CVD during and after active TB disease. We conclude that there is sufficient empirical evidence to justify a greater research emphasis on the syndemic interaction between TB and NCD.
SDGs
Publisher
International Union against Tubercul. and Lung Dis.
Type
journal article