TP53 status and impact on AML prognosis within the ELN 2022 risk classification
Journal
Blood
Journal Volume
142
Journal Issue
23
Pages
2029
Date Issued
2023-12-07
Author(s)
Abstract
This study reports the following: (1) frequency of TP53 comutation within each component of the European LeukemiaNet 2022 acute myeloid leukemia risk classification, (2) relevance of TP53 mutated variant allelic fraction <10%, (3) prognostic impact of -7, -5/del(5q), -17/abn(17p), complex karyotype/monosomal karyotype, or myelodysplasia-related gene mutations with/without mutated TP53.
Type
journal article