Single-Center Experience of Pediatric Heart Transplantation in Taiwan
Journal
Transplantation Proceedings
Journal Volume
38
Journal Issue
7
Pages
2130-2131
Date Issued
2006
Author(s)
Chang C.H.
Ko W.J.
Chu S.H.
Lin F.Y.
Abstract
Heart transplantation (HTx) is a treatment for end-stage heart failure or a complex or inoperable congenital defect. The long-term survival and the adequate donor to recipient body weight (D/R BW) ratio remain to be determined. From March 1995 to May 2004, 14 children (6 months-16 years of age) underwent HTx due to underlying diseases of idiopathic dilated cardiomyopathy (n = 10; 71.4%), congenital heart disease (n = 3; 21.4%), and Kawasaki disease (n = 1; 7.1%). Donor-recipient body weight ratio ranged from 0.89 to 3.9. Big heart syndrome was present in one patient when D/R BW ratio was more than 3. Actuarial survival was 92.9% at 5 years after transplantation. Only the one patient who had Kawasaki disease died due to early primary graft failure. HTx is a feasible method with good long-term survival rates for end-stage heart failure or for complex or inoperable congenital defects. After careful pretransplant evaluation, a high D/R BW ratio (more than 3) is acceptable. ? 2006 Elsevier Inc. All rights reserved.
SDGs
Other Subjects
antihypertensive agent; beta adrenergic receptor blocking agent; cyclosporin; dipeptidyl carboxypeptidase inhibitor; diuretic agent; immunosuppressive agent; lymphocyte antibody; methylprednisolone; tacrolimus; article; body weight; cardiac graft rejection; clinical article; coma; congenital heart disease; congestive cardiomyopathy; donor; female; graft failure; graft recipient; heart transplantation; human; hypertension; hypertensive crisis; infant; male; mucocutaneous lymph node syndrome; postoperative complication; preschool child; priority journal; school child; seizure; survival rate; survival time; Taiwan; treatment outcome; Body Weight; Child; Child, Preschool; Heart Diseases; Heart Transplantation; Humans; Retrospective Studies; Taiwan
Type
journal article