Fluid administration prevents renal dysfunction during hypotension under spinal anesthesia in a rat model
Journal
Acta anaesthesiologica Sinica
Journal Volume
41
Journal Issue
1
Date Issued
2003-03
Author(s)
Abstract
Severe hypotension deteriorates renal functions and renal hemodynamics especially renal cortical blood flow. Systemic hypotension following high level spinal anesthesia may impair renal functions in spite of the blockade of renal sympathetic nerves that may help prevent vasoconstriction. Fluid loading is clinically applied for preventing hypotension but the effects on the changes of renal functions have not been studied. This study was designed to investigate the effects of fluid loading on systemic hemodynamics, renal hemodynamics and functions especially the blood distribution to renal cortex.
Subjects
Anesthesia, spinal | Kidney function tests, microcirculation
Type
journal article