Risk of heart failure in elderly patients with atrial fibrillation and diabetes taking different oral anticoagulants: a nationwide cohort study
Journal
Cardiovascular Diabetology
Journal Volume
22
Journal Issue
1
Date Issued
2023-01-06
Author(s)
Lin, Shu-Man
Liu, Peter Pin-Sung
Lai, Edward Chia-Cheng
Yeh, Jih-I
Hsu, Jin-Yi
Munir, Kashif M
Peng, Carol Chiung-Hui
Huang, Huei-Kai
Loh, Ching-Hui
Abstract
Heart failure (HF) is a critical complication in elderly patients with atrial fibrillation (AF) and diabetes mellitus (DM). Recent preclinical studies suggested that non-vitamin K antagonist oral anticoagulants (NOACs) can potentially suppress the progression of cardiac fibrosis and ischemic cardiomyopathy. Whether different oral anticoagulants influence the risk of HF in older adults with AF and DM is unknown. This study aimed to evaluate the risk of HF in elderly patients with AF and DM who were administered NOACs or warfarin.
Subjects
Atrial fibrillation; Diabetes mellitus; Elderly; Heart failure; Oral anticoagulant
SDGs
Publisher
BMC
Type
journal article