A concise route to phytosphingosine from lyxose
Resource
Tetrahedron Letters 44 (28): 5281-5283
Journal
Tetrahedron Letters
Journal Volume
44
Journal Issue
28
Pages
5281-5283
Date Issued
2003
Author(s)
Abstract
Phytosphingosine was synthesized from the commercially available D-2,3-O-isopropylidene-D-lyxofuranose in 28% overall yield by a six-step procedure. This procedure is expedient and flexible for introduction of other lipid moieties on the phytosphingosine structure to make a variety of derivatives that can support the further exploration of their related biological functions. © 2003 Published by Elsevier Science Ltd.
Type
journal article
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