MR flow analysis in the evaluation of CSF hydrodynamics
Date Issued
2002-07-31
Date
2002-07-31
Author(s)
DOI
902314B002256
Abstract
The purpose of this project was to
determine the CSF production rate in healthy
adults using cine phase-contrast MR imaging
with high temporal and spatial resolutions
plus dedicated image analysis software. 19
healthy adults were imaged. Correlation
coefficient maps were generated based on
pixel-by-pixel analysis of temporal flow
patterns, from which the cross-sectional
aqueduct area was defined using a
region-growing algorithm. The CSF
production rates were calculated using
numerical integration. Operator-dependent
imprecision and effects of temporal
resolution were investigated. The automatic
segmentation approach yielded average CSF
production rate of 332±137 ul/min, in good
agreement with literature values obtained
with invasive ventriculolumbar perfusion
measurements. Mean operator imprecision
was 24.1% (5.8~59.2%). Phase-contrast
MR imaging with sufficient temporal and
spatial resolution is potentially an effective
approach for measuring CSF production rate
on a routine basis.
Subjects
CSF production rate
magnetic
resonance imaging
resonance imaging
phase contrast
Publisher
臺北市：國立臺灣大學電機工程學系暨研究所
Type
report
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