Cancer cell identification by bi-color ZnO and TiO2 nanowires
Journal
Journal of Biophotonics
Journal Volume
10
Journal Issue
1
Pages
92-97
Date Issued
2017
Author(s)
Abstract
Semiconductor nanocomposites provide advantages beyond the capability of typical fluorescent materials for cancer detection. In this work, nanowire-based probes with dual color channels are employed to demonstrate the capacity of cancer cell detection. Purple emitting ZnO/antibody probes are applied to detect cancer cells and meanwhile TiO2/antibody probes with green light emission are applied to identify normal fibroblast cells. A series of quantitative analyses are conducted to verify the correlation between the concentrations of ZnO and TiO2 probes, cell numbers, and peak intensities of the PL spectra. The results provide a quantitative reference for developing nanowire-based cancel cell probes. (Figure presented.). ? 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Subjects
cell detection; nanoprobe; TiO2 nanowires; ZnO nanowires
SDGs
Other Subjects
Cell culture; Cytology; Diseases; Nanoprobes; Nanowires; Probes; Titanium dioxide; Zinc oxide; Cancer cell detection; Cancer cell identification; Cell detection; Fluorescent materials; Nanowire-based probes; Semiconductor nanocomposite; TiO; ZnO nanowires; Cells; nanowire; titanium; titanium dioxide; zinc oxide; diagnostic imaging; human; laser; neoplasm; semiconductor; tumor cell line; Cell Line, Tumor; Humans; Lasers; Nanowires; Neoplasms; Semiconductors; Titanium; Zinc Oxide
Type
journal article