Tigroid background in cytology of hyalinizing clear cell carcinoma of the salivary gland
Journal
Diagnostic Cytopathology
Journal Volume
44
Journal Issue
4
Pages
338-341
Date Issued
2016
Author(s)
Abstract
Hyalinizing clear cell carcinoma (HCCC) is a rare and low grade salivary gland carcinoma with a unique recurrent EWSR1 gene translocation. HCCC most commonly arises from intraoral minor salivary glands and its cytological features have not been well evaluated. We report a 28-year-old man with palatal HCCC and emphasize the "tigroid background" and metachromatic matrix observed in scrape cytology. This "tigroid background," usually associated with glycogen-rich clear cell tumors, is an important cytological feature of HCCC. Awareness of this feature can do great help in pathological research and diagnosis. ? 2015 Wiley Periodicals, Inc.
SDGs
Other Subjects
adult; Article; cancer radiotherapy; case report; clear cell carcinoma; cytodiagnosis; histopathology; human; human tissue; hyalinizing clear cell carcinoma; immunohistochemistry; lymph node dissection; male; maxilla resection; nuclear magnetic resonance imaging; Papanicolaou test; priority journal; salivary gland biopsy; salivary gland carcinoma; tumor invasion; tumor volume; Adenocarcinoma, Clear Cell; cytochemistry; gene expression; gene rearrangement; genetics; metabolism; pathology; salivary gland; Salivary Gland Neoplasms; activating transcription factor 1; ATF1 protein, human; calmodulin binding protein; EWSR1 protein, human; RNA binding protein; Activating Transcription Factor 1; Adenocarcinoma, Clear Cell; Adult; Calmodulin-Binding Proteins; Gene Expression; Gene Rearrangement; Histocytochemistry; Humans; Male; RNA-Binding Proteins; Salivary Gland Neoplasms; Salivary Glands
Publisher
John Wiley and Sons Inc.
Type
journal article