大鼠腦電位信號分佈與MicroPET功能性影像之相關性研究
Date Issued
2005-10-31
Date
2005-10-31
Author(s)
DOI
932213E002066
Abstract
The techniques of functional imaging were
used to provide 3D spatial-temporal mapping of
nociceptive responses during specific neural
activation in brain. We find that the results could
provide invaluable information for basic
neuroscience research. For image experiments,
we do in vivo brain mapping studies with
18F-FDG (Fluorodeoxyglucose) PET (Positron
Emission Tomography) to measure relative
cerebral metabolic rate of glucose (rCMRglc)
and BOLD (Blood Oxygenation Level
Dependent) fMRI (Functional Magnetic
Resonance Imaging) to measure hemodynamic
response. The results not only show the global
somatotopic organization of noxious stimulation
on hindquarters in rats, but also find that the
activated positions were well correlated with
electrophysiological experiments.
used to provide 3D spatial-temporal mapping of
nociceptive responses during specific neural
activation in brain. We find that the results could
provide invaluable information for basic
neuroscience research. For image experiments,
we do in vivo brain mapping studies with
18F-FDG (Fluorodeoxyglucose) PET (Positron
Emission Tomography) to measure relative
cerebral metabolic rate of glucose (rCMRglc)
and BOLD (Blood Oxygenation Level
Dependent) fMRI (Functional Magnetic
Resonance Imaging) to measure hemodynamic
response. The results not only show the global
somatotopic organization of noxious stimulation
on hindquarters in rats, but also find that the
activated positions were well correlated with
electrophysiological experiments.
Subjects
microPET
fMRI
cerebral cortex
thalamus
formalin
rat
Publisher
臺北市:國立臺灣大學醫學工程學研究所
Type
report
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