Accuracy of Biphasic Response, Sustained Improvement and Worsening during Dobutamine Echocardiography in Predicting Recovery of Resting Myocardial Dysfunction after Revascularization: Comparison with Thallium-201 Spect
Resource
ULTRASOUND IN MEDICINE AND BIOLOGY v.27 n.7 pp.925-931
Journal
ULTRASOUND IN MEDICINE AND BIOLOGY
Journal Volume
v.27
Journal Issue
n.7
Pages
925-931
Date Issued
2001
Date
2001
Author(s)
HUANG, POR-JAU
LIN, LUNG-CHUN
Abstract
To evaluate the accuracy of various types of wall motion response during dobutamine echocardiography (DE) in predicting functional recovery after revascularization, we studied 30 patients with stable coronary disease and left ventricular dysfunction by simultaneous DE and Tl-201 reinjection SPECT. Among 480 segments (16 segments/patient), 199 had abnormal wall motion at baseline and 167 were revascularized. The predictive value for recovery of function was 72% for a biphasic response, 61% for sustained improvement, 77% for worsening, and 27% for no change (p<0. 01 vs. each). Biphasic response had a sensitivity of 40% and specificity of 85%. Combining biphasic, sustained improvement and worsening responses, the sensitivity, specificity and accuracy were 76%, 65% and 71%, respectively . For Tl-201 SPECT, they were 90%, 65 % and 78%, respectively. Thus, a biphasic response alone is of low sensitivity. Combination of biphasic, sustained improvement and worsening responses gives an accuracy rate comparable to that of Tl-201 reinjection SPECT in assessing functional recovery.
Subjects
dobutamine
echocardiography
thallium-201 scintigraphy
myocardial viability
Type
journal article