Glycan arrays: biological and medical applications
Resource
Current Opinion in Chemical Biology, 12(1), 86-92
Journal
Current Opinion in Chemical Biology
Journal Volume
12
Journal Issue
1
Pages
86
Date Issued
2008-02
Date
2008
Author(s)
Abstract
Carbohydrates and their conjugates are involved in various biological events, including viral and bacterial infection, the immune response, differentiation and development, and the progression of tumor cell metastasis. Glycan arrays are a new technology that has enabled the high-sensitivity and rapid analysis carbohydrate-protein interaction and contribute to significant advances in glycomics. Glycan arrays use a minute amount of materials and can be used for high-throughput profiling and quantitative analysis and provide information for the development of carbohydrate-based vaccines and new drug discovery.
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