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  4. AN IMMUNE-INFLAMMATORY MODEL OF HUMAN LONGEVITY AND RISKS
 
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AN IMMUNE-INFLAMMATORY MODEL OF HUMAN LONGEVITY AND RISKS

Date Issued
2009
Date
2009
Author(s)
Wang, Jeng-Pang
URI
http://ntur.lib.ntu.edu.tw//handle/246246/188000
Abstract
In this thesis we propose an immune –inflammatory model of human longevity and risks. This thesis will theorize that inflammation as a common pathway and major risk leading to most diseases ( cancer, atherosclerosis, aging-related diseases).and leading to most morbidity and mortality. Anti-inflammatory measures are going to slow or prevent diseases from major health risk, inflammation. And the thesis will also theorize immune phenotype change by available cell proliferation technology would extend current limitation of human longevity.here are many non-chemical approaches in disease prevention and treatments. Of these, electrical bio-feedback is an efficient non-invasive non-chemical approach against inflammation. The nature of non-invasiveness and the efficiency of this approach strengthens the basis for using electrical bio-feedback anti-inflammatory reflex in disease prevention for everyone in daily life. Here, the result showed that HRV-HR is a promising parameter for checking inflammation. Other non-chemical approach are also emphasized in disease prevention and treatment: Eliminate of food antigen, food toxins; Unload mental stress; Eradicate occult infection. And maintain an efficient innate immunity.his thesis also showed that changing immune phenotype is available by cell proliferation technology. The case study on cancer innate immune therapy proves that it is possible and reasonable to use our own innate immunity to treat cancer. Autologous natural killer( NK ) cell transfusions eradicate cancer in pilot study. Terminal hepatocellular carcinoma with portal vein thrombosis totally disappeared with NK cell transfusion as sole treatment. NK cell transfusion prolongs survival in all cases. NK cell transfusion lengthens symptom-free intervals and progression free intervals. It is freely used in any combination therapy. The life quality of patient is much superior to otherwise treated patients. The phenotype change toward NK cell dominance is not only useful in treating cancer is is also useful in prevention against atherosclerosis.The phenotype of NK cell, CD 56 dim played an important role in Coronary Heart Disease. This type of patients has less NK cells. NK is the immune phenotype of healthy longevity. Those with higher NK has favorable endocrine profile, more muscle, more life activity, and less morbidity. Moreover, NK treats and prevents cancer, atherosclerosis, treats variety of infection and brings inflammation back to homeostasis. Abundant NK precursor cells are easily available in the peripheral blood. NK treats and prevents cancer. NK prevents atherosclerosis. NK cell treats variety of infection and brings inflammation back to homeostasis. NK prevalent is the phenotype of healthy ageing. There is easily available abundant NK precursor cells in the peripheral blood , that make change into NK phenotype type present and practical by current proliferation or promotion technology. Thus, we conclude that by having your life immune-friendly way, by lowering the inflammation to prevent diseases, by selecting effective and immune-harmless treatment against diseases, and by promoting or changing into NK prevalent immune phenotype, would be the key for the human being to live beyond the current limitation of human longevity.
Subjects
longevity
diseases pathogenesis
unified theory
immune
inflammation
anti-inflammatory reflex
mental stress
heart rate variability
non-chemical
immune therapy
cell therapy
natural killer cell
cancer
atherosclerosis
ageing
NK prevalent
immune phenotype
SDGs

[SDGs]SDG3

Type
thesis
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ntu-98-D89921038-1.pdf

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