Mechanisms underlying benzyl alcohol cytotoxicity (triamcinolone acetonide preservative) in human retinal pigment epithelial cells
Journal
Investigative ophthalmology & visual science
Journal Volume
52
Journal Issue
7
Date Issued
2011-06-13
Author(s)
Chang, Yi-Sheng
Lin, Chiou-Feng
Wu, Chao-Liang
Kuo, Pao-Ying
Wu, Fong-Sen
Shieh, Chi-Chang
Gean, Po-Wu
Chen, Shur-Tzu
Wu, Wen-Chuan
Tai, Ming-Hong
Tseng, Sung-Huei
Abstract
Benzyl alcohol (BA) is the preservative in triamcinolone acetonide (TA) suspensions, which are used in treating vitreoretinal diseases and during surgery. This paper investigates the molecular mechanisms and signaling pathways underlying BA toxicity in human retinal pigment epithelial (RPE) cells.
Type
journal article