Effect of ropivacaine on endothelium-dependent phenylephrine-induced contraction in guinea pig aorta
Journal
Acta anaesthesiologica Scandinavica
Journal Volume
51
Journal Issue
10
Date Issued
2007-11
Author(s)
Abstract
Previous studies have shown that ropivacaine has biphasic vascular effects, causing vasoconstriction at low concentrations and vasorelaxation at high concentrations. This study was designed to examine the role of the endothelium during accidental intravascular absorption of ropivacaine, and to elucidate the mechanisms responsible.
Subjects
Endothelium | Local anesthetic | Ropivacaine | Vasorelaxation
SDGs
Type
journal article