The serial changes of ghrelin and leptin levels and their relations to weight loss after laparoscopic minigastric bypass surgery
Journal
Obesity Surgery
Journal Volume
18
Journal Issue
1
Pages
84-89
Date Issued
2008
Author(s)
Abstract
Background: The ghrelin and leptin levels have been reported to be correlated with weight loss after bariatric surgery. However, the serial changes of ghrelin and leptin levels after laparoscopic minigastric bypass surgery (LMGBP) have not been reported yet. Therefore, we aimed to evaluate their serial changes and to analyze their relations to weight reduction after LMGBP. Methods: Serial fasting serum leptin and ghrelin concentrations were measured in 68 morbidly obese patients before (M0) and 1 (M1), 3 (M3), 6 (M6), and 12 (M12) months after LMGBP surgery. The correlations between ghrelin, insulin, and leptin concentrations and weight reduction were analyzed. Results: Leptin levels were significantly reduced at 1, 3, 6, and 12 months after surgery, respectively (vs M0, p?
SDGs
Other Subjects
ghrelin; leptin; ghrelin; insulin; leptin; adult; article; body mass; clinical evaluation; controlled study; female; human; laparoscopic surgery; major clinical study; male; morbid obesity; multivariate analysis; preoperative period; priority journal; statistical significance; stomach bypass; treatment duration; weight reduction; blood; laparoscopy; physiology; prediction and forecasting; stomach bypass; time; Adult; Female; Gastric Bypass; Ghrelin; Humans; Insulin; Laparoscopy; Leptin; Male; Obesity, Morbid; Predictive Value of Tests; Time Factors; Weight Loss
Type
journal article