Formation of Pyrrole Derivatives from Heteroatom-Substituted Acetonitriles
Resource
Journal of the Chinese Chemical Society 41 (6): 803-811
Journal
Journal of the Chinese Chemical Society
Date Issued
1994
Author(s)
鄭惠娟
Abstract
Abstract Aminomalononilrile reacted with conjugated carbonyl compounds to give 3 H ‐pyrrolines. Treatment of 2‐cbloro‐2‐phenyllhioacetonitrile with alkenes in the presence of potassium t‐butoxide afforded 1‐pnenylthiocyclopropanecarbonitriles, which reacted with nucleophiles in 1,2‐, 1,4‐ or 1,6‐addition modes. The 1,2‐adducts (cyclopropylimines) rearranged in situ to give substituted pyrroles.
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journal article
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