The effect of statins on the risk of anti-tuberculosis drug-induced liver injury among patients with active tuberculosis: A cohort study
Journal
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Date Issued
2024-04-08
Author(s)
Chang, Chin-Hao
Tsai, Shang-Jie
Abstract
Tuberculosis (TB) remains prevalent worldwide, and anti-TB drugs are associated with drug-induced liver injury (DILI). Statins have pleiotropic effects which may decrease inflammation and achieve immunomodulation. However, few studies have investigated the pleiotropic effects of statins on the risk of DILI. The purpose of this study was to investigate whether statins prevent anti-tuberculosis DILI among active TB patients on standard anti-TB drug therapy.
Subjects
Anti-tuberculosis drug; Drug-induced liver injury; Statin; Tuberculosis
SDGs
Type
journal article