Pulmonary infection caused by nontuberculous mycobacteria in a medical center in Taiwan, 20052008
Journal
Diagnostic Microbiology and Infectious Disease
Journal Volume
72
Journal Issue
1
Pages
47-51
Date Issued
2012
Author(s)
Abstract
The aim of this study was to investigate the epidemiology and clinical characteristics of pulmonary infections caused by nontuberculous mycobacteria (NTM) in a university hospital in Taiwan from 2005 to 2008. During the study period, a total of 312 patients with NTM pulmonary infection were identified. Most patients with NTM pulmonary infection had preexisting pulmonary diseases or malignancies. The incidence (per 100,000 inpatients and outpatients) of patients with NTM isolations (6.67 in 2005 and 9.28 in 2008, P < .0001) from respiratory specimens and the incidence of patients with NTM pulmonary infection (3.54 in 2005 and 4.45 in 2008, P < .0141) increased significantly annually. The most common pathogens in patients with NTM-associated pulmonary infections were Mycobacterium avium complex (n = 110, 35.3%), followed by M. abscessus (n = 66, 21.2%). Incidence (per 100,000 inpatients and outpatients) of patients with pulmonary infections caused by rapidly growing mycobacteria (RGM) also increased significantly (1.06 in 2005 and 2.00 in 2008, P = .008). In conclusion, RGM, especially M. abscessus, had an increasingly important role in NTM pulmonary infections. ? 2012 Elsevier Inc.
SDGs
Other Subjects
adult; article; bacterium isolation; controlled study; female; hospital patient; human; incidence; lung infection; major clinical study; male; Mycobacterium; Mycobacterium abscessus; Mycobacterium celatum; Mycobacterium chelonei; Mycobacterium fortuitum; Mycobacterium gordonae; Mycobacterium intracellulare avium; Mycobacterium kansasii; Mycobacterium phlei; Mycobacterium scrofulaceum; Mycobacterium szulgai; Mycobacterium terrae; outpatient; priority journal; retrospective study; Taiwan; Adult; Aged; Aged, 80 and over; Female; Hospitals, University; Humans; Incidence; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Pneumonia, Bacterial; Risk Factors; Taiwan
Type
journal article