Detection of electrical characteristics of DNA strands immobilized on self-assembled multilayer gold nanoparticles
Journal
Applied Physics Letters
Journal Volume
89
Journal Issue
20
Date Issued
2006
Author(s)
Abstract
Electric detection of DNA in biosensors can be achieved by comparing the differences between the electrical characteristics of biosensors with various concentrations of DNA. This study shows significant electrical property differences between single-stranded DNA and double-stranded DNA by immobilizing DNA strands on biosensor’s self-assembled multilayer gold nanoparticles. The double-stranded DNA has lower electrical resistance than that of single-stranded DNA. These differences can be possibly utilized for DNA identification.
Type
journal article