In vitro studies of functionalized mesoporous silica nanoparticles for photodynamic therapy
Journal
Advanced Materials
Journal Volume
21
Journal Issue
2
Pages
172-177
Date Issued
2009
Author(s)
Abstract
A versatile platform for photodynamic therapy (PDT), mesoporous silica nanoparticles functionalized with protoporphyrin IX (PpIX-MSNs), has been developed. In vitro studies on HeLa cells show high uptake efficiency. Phototoxicity results give both irradiation time- and dosage-dependent cell death events. Because of the ease of incorporating other biomedical functional groups, we believe MSNs would be an ideal platform for biomedical applications.
SDGs
Type
journal article