Comparison of different direct oral anticoagulant regimens in atrial fibrillation patients with high bleeding risk

The optimal dose of direct oral anticoagulants (DOACs) to prevent ischemic stroke (IS) and systemic thromboembolism (STE) in atrial fibrillation (AF) patients with a predisposing bleeding risk remains unclear.

Subjects

Atrial fibrillation; Comparative effectiveness and safety; Direct oral anticoagulants; Dose regimens; High bleeding risk; Moderate thrombosis risk