Esophageal adenocarcinoma arising from Barrett's epithelium in Taiwan
Journal
Journal of the Formosan Medical Association
Journal Volume
106
Journal Issue
8
Pages
664-668
Date Issued
2007
Author(s)
Abstract
The prevalence of Barrett's esophagus (BE) in Eastern countries is rising to match the prevalence in the West. However, a corresponding trend of BE-associated adenocarcinoma has yet to be observed in Asia. Historically, adenocarcinoma complicating BE has been considered a rare event in Taiwan. In the present report, we collected three Taiwanese cases of esophageal adenocarcinoma arising from BE. The first case was a 37-year-old man with an advanced cancer that developed on pre-existing BE after a 3-year interval without endoscopic surveillance. The second case was a 63-year-old man who presented with odynophagia and was found to have an ulcerative tumor centered on the characteristic Barrett's mucosa. The final case was a 44-year-old man who presented with gradual-onset dysphagia and weight loss, without typical reflux symptom. Our report emphasizes the need for an updated epidemiologic study to determine the incidence of BE-associated adenocarcinoma in Taiwan. ? 2007 Elsevier & Formosan Medical Association.
SDGs
Other Subjects
barium; cisplatin; advanced cancer; article; Barrett esophagus; case report; dysphagia; esophageal adenocarcinoma; esophagoscopy; esophagus mucosa; esophagus ulcer; gastroesophageal reflux; human; human tissue; male; odynophagia; Taiwan; weight reduction
Publisher
Scientific Communications International Ltd
Type
journal article