Assessing the population transmission dynamics of tilapia lake virus in farmed tilapia
Journal
Journal of Fish Diseases
Journal Volume
41
Journal Issue
9
Pages
1439-1448
Date Issued
2018
Author(s)
Abstract
A novel virus, tilapia lake virus (TiLV), has been identified as a key pathogen responsible for disease outbreak and mass mortality of farmed tilapia. We used a deterministic susceptible-infectious-mortality (SIM) model to derive key disease information appraised with published TiLV-induced cumulative mortality data. The relationship between tilapia mortality and TiLV exposure dosages was described by the Hill model. Furthermore, a disease control model was proposed to determine the status of controlled TiLV infection using a parsimonious control reproduction number (RC)-control line criterion. Results showed that the key disease determinants of transmission rate and basic reproduction number (R0) could be derived. The median R0 estimate was 2.59 in a cohabitation setting with 2.6?×?105?TCID50?fish?1 TiLV. The present RC-control model can be employed to determine whether TiLV containment is feasible in an outbreak farm by quantifying the current level of transmission. The SIM model can then be applied to predict what additional control is required to manage RC?<?1. We offer valuable tools for aquaculture engineers and public health scientists the mechanistic-based assessment that allows a more rigorous evaluation of different control strategies to reduce waterborne diseases in aquaculture farming systems. ? 2018 John Wiley & Sons Ltd
Subjects
disease transmission dynamics; modelling; tilapia; tilapia lake virus (TiLV)
Other Subjects
Article; basic reproduction number; cohabitation; controlled study; disease control; epidemic; host susceptibility; mathematical model; mortality; nonhuman; Oreochromis niloticus; pisciculture; population density; population dynamics; population size; Tilapia lake virus; virus; virus infection; virus transmission; animal; aquaculture; disease predisposition; fish disease; lake; mortality; orthomyxovirus infection; theoretical model; Tilapia; transmission; veterinary medicine; virology; Animals; Aquaculture; Disease Susceptibility; Fish Diseases; Lakes; Models, Theoretical; Orthomyxoviridae Infections; Tilapia
Type
journal article