Case Report: Primary Aldosteronism Due to Bilateral Aldosterone-Producing Micronodules With HISTALDO Classical and Contralateral Non-Classical Pathology
Journal
Frontiers in Endocrinology
Journal Volume
13
Pages
816754
Date Issued
2022
Author(s)
Chen, Yi-Ju
Peng, Kang-Yung
Liao H.-W.
(TAIPAI) Study Group
Abstract
Background: Non-classical multiple aldosterone-producing micronodules/nodules (mAPM/mAPN) could be the pathogenesis of primary aldosteronism (PA). The co-existence of mAPM with adenomas harboring somatic mutations has not previously been reported. Methods: We presented a PA patient with bilateral mAPM and concomitant autonomous cortisol secretion (ACS). Results: L206R mutation. Conclusion: In a PA patient with concomitant ACS, bilateral APM could coexist with both histopathologically classical and non-classical PA adenomas, each with different somatic mutations. The presence of ACS could lead to the misinterpretation of AVS results.
SDGs
Publisher
Frontiers Media S.A.
Type
journal article