Capillary hemodynamics on nailfold under physiological variation:temperature.centella & low intensity laser
Date Issued
2006
Date
2006
Author(s)
Cheng, Chiun-Yuan
DOI
zh-TW
Abstract
Great finger nail matrix capillaries were continuously examined in 35 normal volunteers with the Lippolis capillaroscope . Under the increasing of body temperature red blood cell velocities(RBCV) were raised from 0.35±0.27mms-1 to 0.67±0.20mms-1 in 80.2% amounts of flowing cappilaries and 61.0% amounts of total capillaries. All subjects were treated with total triterpenic fraction of Centella asiatica (TTFCA) (0.1g on 1cm2 of nail finger), a drug active on microcirculation and capillary permeability. With the absorption of TTFCA, real-time images monitored on which the amounts of capillaries could be observed were raised were clearer and RBCVs were raised from 0.38±0.29mms-1 to 0.37±0.22 mms-1 in 24.7% amounts of flowing capillaries and 18.8% amounts of total capillaries. Under the Diode laser (low level laser irradiation) scanning, RBCVs were raised from 0.37±0.24mms-1 to 0.45±0.30 mms-1 in 95.1% amounts of flowing capillaries and 72.3% amounts of total capillaries. Both TTFCA and Diode laser were useful on nail fold by improving microcirculation.
.
The present method provided a less expensive system with which capillaries were measured relatively parallel to the skin for some period, the RBC particle traces and the corresponding velocity gave a better view of the vessel wall interaction, path irregularity, and upstream influence of pulsation. The present apparatus can be used for the capillaries on the nail fold of fingers, thus its clinical applications to any kind of microcirculation study is feasible.
Subjects
微循環
紅血球流速
低能量雷射
甲襞
hemodynamics
nailfold
LLLI
rbcv
Type
thesis
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