Clinical characteristics of patients with segmental renal infarction
Journal
Nephrology
Journal Volume
11
Journal Issue
4
Pages
336-340
Date Issued
2006
Author(s)
Abstract
Background: Renal infarction is usually an underestimated disease due to its rare and non-specific presentations; the renal survival of these patients is not well studied. The aim of the present analysis is to study the clinical features and outcome in patients who had documented renal infarction. Methods: Twenty-two patients (12 men and 10 women, mean age of 57.7 ± 3.44 years (28.4-83.3 years)) with image-confirmed segmental renal infarction in the past 15 years were enrolled. All patients were followed up at outpatient department with a median of 4 years (1-14 years). Initial and follow-up clinical characteristics and laboratory results were recorded. Results: The most common underlying disease was cardiovascular disease. Renal infarction often presented with non-specific symptoms, including flank pain (55%), vague abdominal pain (50%), nausea/vomiting (46%) and fever (27%).The levels of leucocytes, lactate dehydrogenase, blood urea nitrogen and serum creatinine were all elevated at admission. The early diagnosis group (12/22) had more obvious flank pain, nausea/vomiting (P < 0.001) and higher alanine transaminase (P = 0.02). It also predisposed to undergo antiplatelet or anticoagulant therapy (all P < 0.04). During follow up, there was no recurrence in the whole study group, and a trend of better recovery of renal function was noted in the early diagnosis group. Conclusion: The serum creatinine level correlates with longer hospitalization length (P < 0.05). As regards long-term prognosis, no definite factor or treatment was found to have significant effect in segmental renal infarction patients. However, early diagnosis and early initiation of treatment seems to have a positive effect on future renal outcome. ? 2006 The Authors.
SDGs
Other Subjects
acetylsalicylic acid; alanine aminotransferase; anticoagulant agent; antithrombocytic agent; creatinine; heparin; lactate dehydrogenase; low molecular weight heparin; nitrogen; urea; urokinase; warfarin; abdominal pain; adult; alanine aminotransferase blood level; anticoagulant therapy; article; cardiovascular disease; clinical article; clinical feature; controlled study; convalescence; correlation analysis; creatinine blood level; early diagnosis; female; fever; flank pain; follow up; gastrointestinal hemorrhage; hospital admission; hospitalization; human; kidney infarction; laboratory test; lactate dehydrogenase blood level; length of stay; leukocyte count; male; medical documentation; nausea and vomiting; outcome assessment; outpatient department; priority journal; prognosis; recurrent disease; symptom; urea nitrogen blood level; Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Infarction; Kidney; Male; Middle Aged; Retrospective Studies
Type
journal article