行政院國家科學委員會專題研究計畫成果報告:台灣地區癲癇症臨床及流行病學研究
Date Issued
2000
Date
2000
Author(s)
劉宏輝
DOI
892314B002145
Abstract
A retrospective cohort with IS is obtained from one medical center to identify 69 IS cases (from 1985 to 1997), This cohort in conjunction with claim data from national health insurance was used to estimate prevalence, and incidence. A hospital-based case-control study was conducted to find out risk factors. Only 25 out of 69 IS are completed by telephone interview with questionnaire. A total of 106 subjects and 139 subjects in Disease Control and Normal Control, respectively were obtained as comparison groups. Unconditional logistic regression was used to calculate odds ratios and 95% CI. Incidence and prevalence (aged 0-9 years) are estimated as 0.06 per thousand live births and 0.05 per thousand. Significant prenatal factors include tuberous sclerosis, cerebral palsy, and other congenital anomalies. Neonatal asphyxia (perinatal factor) significantly accounts for the occurrence of IS. Developmental delay before onset of disease (postnatal factor) is highly associated with IS. Information obtained in this study not only make a clear understanding of disease burden of IS in this society but clarify more etiology of IS than before.
Publisher
臺北市：國立臺灣大學醫學院神經科
Type
journal article
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