A Double-Blind, Randomized, Controlled Trial of Lovastatin in Early-Stage Parkinson's Disease
Journal
Movement disorders : official journal of the Movement Disorder Society
Date Issued
2021-01-15
Author(s)
Chang, Chin-Hao
Chen, Yi-Chieh
Chao, Ying-Ting
Huang, Tse-Le
Abstract
Recent evidence indicates that lipophilic statins have a neuroprotective benefit in animal models of Parkinson's disease (PD). The objective of this study was to evaluate whether lovastatin has the potential to slow motor symptom progression in patients with early-stage PD.
Subjects
Parkinson's disease; lovastatin; trial
SDGs
Other Subjects
6 fluorodopa f 18; alanine aminotransferase; aspartate aminotransferase; creatine kinase; dopamine; dopamine receptor stimulating agent; hemoglobin A1c; low density lipoprotein; mevinolin; placebo; triacylglycerol; mevinolin; adult; alanine aminotransfera
Type
journal article