行政院國家科學委員會專題研究計劃成果報告:原發性隅角閉鎖性青光眼的研究
Date Issued
1999
Date
1999
Author(s)
洪伯廷
DOI
882314B002370
Abstract
(I) Prevalence of PACG and its blindness are increasing from increasing world geriatric population, and socio-economic ievelopment. Current diagnostic criteria is introduced, emphasizing ocular image studies, by stereo photographic study of optic nerve, and Ascan ultrasonography. A screen procedure is proposed. The risk/benefit ratio is also emphasized for early treatment of PACG.
(II) In this study, we tested the effectiveness of latanoprost as an intraocular pressure (lOP) lowering agent in cases of residual PACG. Twenty-six eyes of 26 PACG patients with persistently elevated lOP after iridectomy, despite treatment with conventional TOP lowering drugs (beta blockers and pilocarpine) were included. Latanoprost (¡¥.005%, one drop daily, was added adjunctively to all eyes. The TOP decreased by about 21% (p < 0.005) during the first 3 months, and showed a rec.uction of about 36% at the end of 1 year. At the 1-year follow up, the JO? was well controlled (below 20 mmHg) in all eyes. These findings show that, in combination with beta blockade and pilocarpine, latanoprost can ameliorate residual PACG.
Subjects
PACG
prevalence
optic nerve atrophy
drugs
Publisher
臺北市：國立臺灣大學醫學院眼科
Type
journal article
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