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  4. Low-cost and rapid fabrication of metallic nanostructures for sensitive biosensors using hot-embossing and dielectric-heating nanoimprint methods
 
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Low-cost and rapid fabrication of metallic nanostructures for sensitive biosensors using hot-embossing and dielectric-heating nanoimprint methods

Journal
Sensors (Switzerland)
Journal Volume
17
Journal Issue
7
Pages
-
Date Issued
2017
Author(s)
Lee, K.-L.
Wu, T.-Y.
Hsu, H.-Y.
Yang, S.-Y.
Wei, P.-K.
SEN-YEU YANG  
DOI
10.3390/s17071548
URI
https://scholars.lib.ntu.edu.tw/handle/123456789/448144
URL
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021685990&doi=10.3390%2fs17071548&partnerID=40&md5=90b5866fc2b8e595f9ce150c40436f2a
Abstract
We propose two approaches-hot-embossing and dielectric-heating nanoimprinting methods-for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2.7 nm in the visible light region. The periodic aluminum nanostructure achieves a figure of merit of 150, and an intensity sensitivity of 29,345%/RIU (refractive index unit). The rapid fabrication is also achieved by using radio-frequency (RF) sensitive plastic films and a commercial RF welding machine. The dielectric-heating, using RF power, takes advantage of the rapid heating/cooling process and lower electric power consumption. The fabricated capped aluminum nanoslit array has a 5 nm Fano linewidth and 490.46 nm/RIU wavelength sensitivity. The biosensing capabilities of the metallic nanostructures are further verified by measuring antigen-antibody interactions using bovine serum albumin (BSA) and anti-BSA. These rapid and high-throughput fabrication methods can benefit low-cost, highly sensitive biosensors and other sensing applications.
SDGs

[SDGs]SDG3

[SDGs]SDG9

Type
journal article

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