Assessing efficacy of antiviral therapy for COVID-19 patients: A case study on remdesivir with bayesian synthesis design and multistate analysis
Journal
Journal of the Formosan Medical Association
Journal Volume
120 Suppl 1
Date Issued
2021-06
Author(s)
Yen, Jui-Yi
Hsu, Chen-Yang
Yen, Amy Ming-Fang
Abstract
A synthesis design and multistate analysis is required for assessing the clinical efficacy of antiviral therapy on dynamics of multistate disease progression and in reducing the mortality and enhancing the recovery of patients with COVID-19. A case study on remdesivir was illustrated for the clinical application of such a novel design and analysis.
Subjects
Antiviral therapy; Bayesian synthesis sequential design; COVID-19; Clinical efficacy; Remdesivir
SDGs
Other Subjects
remdesivir; adenosine phosphate; alanine; antivirus agent; remdesivir; antiviral therapy; Article; Bayes theorem; controlled study; coronavirus disease 2019; death; follow up; high risk patient; high risk population; hospitalization; human; low risk population; major clinical study; risk factor; drug therapy; treatment outcome; Adenosine Monophosphate; Alanine; Antiviral Agents; Bayes Theorem; COVID-19; Humans; SARS-CoV-2; Treatment Outcome
Type
journal article