Homocystinuria presenting as fatal common carotid artery occlusion
Journal
Pediatric Neurology
Journal Volume
15
Journal Issue
2
Pages
159-162
Date Issued
1996
Author(s)
Abstract
A patient with homocystinuria presenting with fatal cerebral infarction that resulted from left common carotid artery occlusion is reported. This 13- year-old, healthy and intelligent girl presented with progressive cerebral infarction. Angiography revealed total occlusion of the left common carotid artery and stenosis of the right common carotid artery. Distal stenosis of bilateral vertebral arteries was also observed. Initially Takayasu arteritis with unusual manifestation was considered. However, later investigations revealed homocystinuria was the underlying cause. The sudden onset of fatal stroke as the initial clinical presentation of homocystinuria, as observed in this previous healthy teenager, is noteworthy. We suggest metabolic screening for homocystinuria when treating a patient with unusual vascular lesions.
SDGs
Other Subjects
cyanocobalamin; methylprednisolone; nitroprusside sodium; pyridoxine; adolescent; aorta arch syndrome; aortography; article; brain infarction; carotid arteriography; carotid artery obstruction; case report; clinical feature; common carotid artery; computer assisted tomography; electroencephalogram; female; homocystinuria; human; medical record; neurologic examination; physical examination; priority journal
Publisher
Elsevier Inc.
Type
journal article