Curved Surface Induced Microdroplet Actuation System and Its Biochemistry Application
Date Issued
2008
Date
2008
Author(s)
Lo, Chien-Wei
Abstract
We developed a novel method of droplets actuation simply by using the surface tension distribution of a curved surface of hydrophobic plastic membrane and a flat hydrophilic glass substrate without applying outer electrical or magnetic power. There are two basic modes of actuation : droplet moving with probe and droplet homing and three application modes : mixing of powder droplets, droplet ratio splitting and multiple chips simultaneous actuation. The basic three-dimensional explanation of two basic modes has been established and the actual velocity relationship between probes and droplets had been found and the experimental performance data for de-ionized water of the two basic modes and droplets mixing and split had been worked out. Since there is no need of outer power source, the material inside the droplet is stable and can be applied on stably transporting or manipulating droplets carrying polar or ionized particles such as DNA or protein molecules and since multiple chips can be simply actuated simultaneously by the same probe sets, just like the concept of DNA microarray and the chip of actuation need no microstructure thus the cost is extremely low, with the low cost of batch laser drilling technique and the double-sided tape spacer, the potential of industry application will be infinity.
Subjects
Curved surface
Moving with probe
Homing, Ratio splitting
Multiple chips simultaneous actuation
Type
thesis
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