Early Methylprednisolone Treatment Can Stabilize the Blood-Optic Nerve Barrier in a Rat Model of Anterior Ischemic Optic Neuropathy (rAION)
Journal
Investigative ophthalmology & visual science
Journal Volume
58
Journal Issue
3
Date Issued
2017-03-01
Author(s)
Abstract
We investigated whether methylprednisolone (MP) treatment halting retinal ganglion cell (RGC) death and having anti-inflammatory effect over a narrow therapeutic window affects the integrity of the blood-optic nerve barrier (BOB) in a rat model of ischemic optic neuropathy (rAION).
Subjects
Blood-optic nerve barrier | Methylprednisolone | Optic nerve | Rat model of ischemic optic neuropathy | Retinal ganglion cell
SDGs
Type
journal article