Nutritionally Variant Streptococcal Infections at a University Hospital in Taiwan: Disease Emergence and High Prevalence of β-Lactam and Macrolide Resistance
Journal
Clinical Infectious Diseases
Journal Volume
38
Journal Issue
3
Pages
452-455
Date Issued
2004
Author(s)
Abstract
From January 1993 to December 2002, 28 patients with nutritionally variant streptococci (NVS) infections were treated at a university hospital in Taiwan. Twelve (43%) of these patients had various underlying malignancies, and 7 (25%) had underlying valvular heart diseases. Nine patients (32%) had infective endocarditis, and 9 (32%) had primary bacteremia. The deaths of 7 patients (25%) were directly related to NVS infection. Among the 28 isolates recovered from these patients, 50% were not susceptible to penicillin, 33% were not susceptible to cefotaxime, and 93% were not susceptible to azithromycin.
Other Subjects
azithromycin; beta lactam antibiotic; cefotaxime; macrolide; penicillin G; adolescent; adult; aged; antibiotic resistance; article; bacteremia; bacterial endocarditis; bacterium isolation; child; death; female; human; male; nonhuman; priority journal; Streptococcus infection; Taiwan; university hospital; valvular heart disease; Adolescent; Adult; Aged; Azithromycin; beta-Lactam Resistance; Cefotaxime; Child; Drug Resistance, Bacterial; Female; Hospitals, University; Humans; Macrolides; Male; Microbial Sensitivity Tests; Middle Aged; Streptococcal Infections; Streptococcus; Taiwan
Type
journal article