Hemodynamic Study of Left Ventricular Assist Device during Laparoscopy in Canine Model
Journal
Taiwan Veterinary Journal
Journal Volume
35
Journal Issue
3
Pages
153-161
Date Issued
2009
Author(s)
Abstract
To understand the hemodynamic changes and interaction between the operation of left ventricular assist device (LVAD) and laparoscopy, a small Tai-Ta centrifugal impeller pump was applied in a canine model, in which 6 healthy dogs weighted 14-20kg were used. Blood flows in the aortic (AO) arch, common carotid artery (CCA), coronary artery (CA), femoral artery (FA), and the LVAD outlet were measured simultaneously with the arterial blood pressure (ABP), the pump outflow pressure (POP), and the electrocardiograph (ECG). After the centrifugal impeller pump operated, a fluctuated flow was produced by LVAD according to the cardiac cycles. The waveform of ABP and the flows of CA, CCA, and FA had mild change after systole due to the influence from LVAD flow. After abdominal insufflations the LVAD flow increased in 4 cases and decreased in another 2 cases, the CA flow increased in 3 cases and decreased in 1 case, the CCA flow increased in 2 cases and decreased in 4 cases, the FA flow decreased in all 4 cases. However, by increasing the rotational speed of pump to make LVAD flow more than 50% of total cardiac output, both the pump flow and total cardiac output increased, and the affected CA and CCA flows were also increased. These results indicated that the centrifugal impeller pump could safely operate as a LVAD without significant hemodynamic compromise when intervened with laparoscopy.
Subjects
left ventricle assist device
laparoscopy
canine model
hmodynamics
Type
journal article