Targeted sequencing of taiwanese breast cancer with risk stratification by the concurrent genes signature: A feasibility study
Journal
Journal of Personalized Medicine
Journal Volume
11
Journal Issue
7
Date Issued
2021
Author(s)
Abstract
mutations were further revealed by multivariate Cox's regression (hazard ratios: 29.4 and 16.1). In addition, we identified several significantly mutated or pathogenic variants associated with differentially expressed signature genes. The feasibility of targeted sequencing in combination with concurrent genes risk stratification was ascertained. Future study to validate clinical applicability and evaluate potential actionability for Taiwanese breast cancers should be initiated.
SDGs
Publisher
MDPI
Type
journal article