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Hepatocellular carcinoma after treatment cessation in non-cirrhotic HBeAg-negative chronic hepatitis B: A multicentre cohort study
Journal
Liver international : official journal of the International Association for the Study of the Liver
Journal Volume
42
Journal Issue
3
Pages
541
End Page
550
Date Issued
2022-03
Author(s)
Papatheodoridi, Margarita
Hadziyannis, Emilia
Liao, Chun-Hsun
Orfanidou, Αfroditi
Zachou, Kalliopi
Kourikou, Anastasia
Gatselis, Nikolaos
Manolakopoulos, Spilios
Dalekos, George
Hadziyannis, Stephanos
Papatheodoridis, George V
Abstract
Scarce data exist on the effect of nucleos(t)ide analogue (NA) discontinuation on hepatocellular carcinoma (HCC) risk in HBeAg-negative chronic hepatitis B (CHBe-). Therefore, we assessed whether HCC risk is increased in non-cirrhotic CHBe- patients who discontinue compared to those remaining on NAs.
Subjects
discontinuation; entecavir; liver cancer; nucleoside analogue; tenofovir
Publisher
WILEY
Type
journal article