Epicutaneous sensitization with a protein antigen induces Th17 cells
Journal
Journal of dermatological science
Journal Volume
54
Journal Issue
3
Pages
192
Date Issued
2009-06
Author(s)
Abstract
Th17 is a newly identified effector T cell lineage which plays a central role in many human inflammatory diseases and experimental animal models. Epicutaneous sensitization with a protein antigen has been proven to induce a Th2-predominant immune response and lead to development of atopic diseases in a murine protein-patch model.
Subjects
Th17 cells; Epicutaneous sensitization; Protein antigen; Allergy
SDGs
Other Subjects
antigen; hapten; interleukin 17; interleukin 22; irritant agent; ovalbumin; superantigen; toll like receptor 2; toll like receptor 3; toll like receptor 4; toll like receptor 5; toll like receptor 7; toll like receptor 9; animal cell; animal experiment; article; Bagg albino mouse; C57BL 6 mouse; CD4+ T lymphocyte; cell culture; controlled study; enzyme linked immunosorbent assay; enzyme linked immunospot assay; enzyme regulation; female; genetics; in vitro study; lymph node cell; mouse; nonhuman; priority journal; skin sensitization; supernatant; Th17 cell; Animals; Antigens; CD4-Positive T-Lymphocytes; Cytokines; Female; Hypersensitivity, Immediate; Interleukin-17; Interleukins; Ligands; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Skin; T-Lymphocytes, Helper-Inducer; Toll-Like Receptors
Publisher
ELSEVIER IRELAND LTD
Type
journal article