Perspectives and outlook from HEP window on the universe

This brief review grew out from the HEP concluding talk of the 25th Anniversary of the Rencontres du Vietnam, held in August 2018, at Quy Nhon. The first two-thirds gives a summary and highlights, or snapshot, of High Energy Physics at the end of Large Hadron Collider (LHC) Run 2. It can be viewed as the combined effort of the program organizers, the invited plenary speakers, and finally filtered into the present mosaic. It certainly should not be viewed as comprehensive. In the second one-third, a more personal perspective and outlook is given, including my take on the flavor anomalies, and why the next three years, the period of Long Shutdown 2 plus first year (or more) of LHC Run 3, would be bright and flavorful, with much hope for uncovering New Physics. We advocate extra Yukawa couplings as the most likely, next, New Physics to be tested, the effect of which is already written in our Matter Universe. ? 2019 World Scientific Publishing Company.