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  4. Studies on the Chemical Constituents of Derris laxiflora Benth.
 
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Studies on the Chemical Constituents of Derris laxiflora Benth.

Date Issued
2007
Date
2007
Author(s)
Chiu, Hsi-Lin
DOI
zh-TW
URI
http://ntur.lib.ntu.edu.tw//handle/246246/51699
Abstract
Derris laxiflora Benth., a member of the Leguminosae, endemic in Taiwan, distributed at altitudes of under 1000 meters. It's roots and the stems were once used as the agricultural pesticide. Taiwan aboriginals also took root's juice to poison fish. The components can be used to poison fish, but innocuous to mammalian. The methanol extract from D. laxiflora was concentrated to give a residue which was partitioned between ethyl acetate and H2O. The ethyl acetate layer was separated by column chromatography on silica gel, preparative thin layer chromatography, flash column chromatography, and high performance liquid chromatography (HPLC) to give one hundred and forty three compounds, including 13 aromatic compounds, 5 chlorophylls, 25 flavonoids, 13 isoflavonoids, 12 lignans, 10 pterocarpans, 21 steroids, 32 triterpenoids, and 12 other type compounds. Known compounds were identified by IR, NMR, and Mass spectral analysis and comparison with those of authentic samples or data reported in literatures. Structures of new compounds were further elucidated by 2D NMR spectral and chemical methods. Among these isolated compounds, there are fifteen new compounds, and seven of them were isolated for the first time from natural sources.
Subjects
疏花魚藤
魚藤屬
類黃酮
三萜
類
紫檀烷
固醇類
Derris laxiflora
Derris
flavonoid
triterpenoid
pterocarpan
steroid
Type
thesis
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