Increase in B19 viral load prior to relapse of anaemia in an AIDS patient with persistent B19 infection
Journal
Journal of Infection
Journal Volume
43
Journal Issue
2
Pages
150-152
Date Issued
2001
Author(s)
Abstract
Anaemia caused by persistent parvovirus B19 infection can be remitted by intravenous immunoglobulin (IVIG) treatment. However, maintenance IVIG therapy is required in some AIDS patients as well as patients with combined immuno-deficiency because of relapse of anaemia. We used a simple semi-quantitative polymerase chain reaction (PCR) method to trace plasma B19 viral load after administration of IVIG. We noted that the rebound of B19 viral load occurred 6 weeks prior to detection of anaemia. This method may be helpful in determining the interval of maintenance IVIG therapy. ? 2001 The British Infection Society.
SDGs
Other Subjects
ciprofloxacin; clarithromycin; cotrimoxazole; ethambutol; immunoglobulin; isoniazid; lamivudine; pyrazinamide; rifampicin; saquinavir; zalcitabine; zidovudine; acquired immune deficiency syndrome; adult; anemia; article; blood transfusion; case report; erythema infectiosum; human; Human immunodeficiency virus infection; lung tuberculosis; maintenance therapy; male; mycobacteriosis; Parvovirus; persistent infection; Pneumocystis pneumonia; polymerase chain reaction; relapse; virus load
Publisher
W.B. Saunders Ltd
Type
journal article