99mTc ECD and 99mTc TRODAT-1 SPECT in Hashimoto encephalopathy
Journal
Clinical Nuclear Medicine
Journal Volume
37
Journal Issue
4
Date Issued
2012
Abstract
Hashimoto encephalopathy is characterized by cognitive impairment and other neurologic symptoms, including seizure, myoclonus, tremor, ataxia, parkinsonism, and psychiatric disorders. The presence of serum antithyroglobulin antibody and/or antimicrosomal antibody is always found, and the response to steroid treatment is usually promising. We report a case of a 41-year-old woman with Hashimoto encephalopathy, with a unique presentation as left hemichorea and left hemiparkinsonism. Both ECD ( 99mTc ethyl cysteinate dimer) and SPECT ( 99mTc TRODAT-1 single photon emission computed tomography) images demonstrated significantly decreased tracer uptake in the right striatum. These images could provide us evidence of striatum impairment in movement disorders of Hashimoto encephalopathy. ? 2012 by Lippincott Williams & Wilkins.
Subjects
99mTc ECD; 99mTc TRODAT-1; choreic movement; Hashimoto encephalopathy; parkinsonism
SDGs
Other Subjects
99mTc ethyl cysteinate dimer; [2 [[2 [[[3 (4 chlorophenyl) 8 methyl 8 azabicyclo[3.2.1]oct 2 yl]methyl](2 mercaptoethyl)amino]ethyl]amino]ethanethiolato]oxotechnetium tc 99m; radiopharmaceutical agent; unclassified drug; cysteine; cysteine ethyl ester tc 99m; diagnostic agent; drug derivative; technetium complex; technetium Tc 99m TRODAT 1; technetium Tc 99m TRODAT-1; tropane derivative; adult; article; case report; chorea; clinical feature; cognitive defect; female; Hashimoto encephalopathy; human; memory disorder; parkinsonism; radioactivity; single photon emission computer tomography; brain disease; Hashimoto disease; pathology; pathophysiology; scintiscanning; Adult; Brain Diseases; Cysteine; Female; Hashimoto Disease; Humans; Organotechnetium Compounds; Tomography, Emission-Computed, Single-Photon; Tropanes
Type
journal article