Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures
Journal
Advanced Materials
Journal Volume
25
Journal Issue
11
Pages
1547-1551
Date Issued
2013
Author(s)
Hou, S.
Abstract
A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.
Type
journal article