Modelling Mechanical Communication and Collective Motion of Cancer Cells
Journal
2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS)
Part Of
2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems, SCIS and ISIS 2024
Start Page
1
End Page
5
ISBN (of the container)
9798350373332
ISBN
9798350373332
Date Issued
2024-11-09
Author(s)
Abstract
Understanding the communication mechanisms that drive collective behaviors in cancer is crucial for elucidating cancer progression and metastasis. To investigate communication mechanisms and their impacts on collective cell behaviors in can-cer, our previous study employed time-lapse imaging techniques on cancer cells placed on substrates containing fluorescent beads. In these experiments, we observed bead movements that reflect mechanical cell communication through substrate dynamics and collective cell motions. In this study, our objective is to develop a computational model to reproduce the experimental observations from our previous study. We demonstrated that the model developed in this paper substantiated previous experimental findings and established a foundation for further investigations into the communication mechanisms and collective behaviors in cancer.
Event(s)
Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems, SCIS and ISIS 2024, Himeji. 9 November 2024 through 12 November 2024. Code 204675
Publisher
IEEE
Type
conference paper