Neurosarcoidosis Affecting the Spinal Cord
Journal
Journal of the Formosan Medical Association
Journal Volume
109
Journal Issue
9
Pages
676-679
Date Issued
2010
Author(s)
TSAI, CHUNG-FEN
YIP, PING-KEUNG
Abstract
Sarcoidosis is a chronic inflammatory disease that involves multiple systems. Complications in the nervous system are rare, especially in Asia. This report describes an unusual case of neurosarcoidosis affecting the spinal cord and other systems in a 53-year-old Taiwanese women patient. The patient presented with subacute onset of right arm radicular pain followed by quadriparesis. Magnetic resonance imaging revealed a hyperintense lesion on T2WI in the cervical spinal cord. The patient also had a history of facial neuropathy, bilateral parotid enlargement, intrathoracic lymphadenopathy, hypercalcemia, nephrocalcinosis, and renal function impairment. Parotid gland biopsy showed granulomatous lesion with multinucleated giant cells. Sarcoidosis was diagnosed after other possibilities were excluded. Oral steroid treatment resulted in initial significant clinical improvement. Awareness of the systemic and neurological presentations of sarcoidosis can prompt the correct diagnosis and treatment. ? 2010 Formosan Medical Association & Elsevier.
Subjects
Neurosarcoidosis; Sarcoidosis; Taiwan
SDGs
Other Subjects
gadolinium; prednisolone; steroid; glucocorticoid; prednisolone; adult; article; Bell palsy; biopsy; case report; cervical spinal cord injury; computer assisted tomography; echography; female; granulomatosis; human; hypercalcemia; hyperreflexia; hyporeflexia; intrathoracic lymphadenopathy; kidney calcification; kidney dysfunction; kidney failure; laboratory test; lymphadenopathy; nephrolithiasis; neurologic examination; nuclear magnetic resonance imaging; paraplegia; parotid enlargement; parotid gland biopsy; physical examination; polyneuropathy; quadriplegia; radicular pain; sarcoidosis; spinal cord disease; spinal cord sarcoidosis; Taiwan; middle aged; pathology; sarcoidosis; spinal cord; spinal cord disease; spinal root; treatment outcome; Female; Glucocorticoids; Humans; Magnetic Resonance Imaging; Middle Aged; Prednisolone; Sarcoidosis; Spinal Cord; Spinal Cord Diseases; Spinal Nerve Roots; Taiwan; Treatment Outcome
Type
journal article